Ljudska endogena retrovirusna K endopeptidaza
Ljudska endogena retrovirusna K endopeptidaza (EC 3.4.23.50, ljudska endogena retrovirusna K10 endopeptidaza, endogena retrovirusna HERV-K10 proteaza, ljudki endogeni retrovirusni K retropepsin, HERV K10 endopeptidaza, HERV K10 retropepsin, HERV-K PR, HERV-K proteaza, HERV-K113 proteaza, ljuska endogena retrovirusna K113 proteaza, ljuski retrovirusni K10 retropepsin) je enzim.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Ljudska endogena retrovirusna K endopeptidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.23.50 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Modifikacija autentičnog HIV-1 PR mesta prepoznavanja i oslobađanje maturisanih p17 matriks i p24 kapsidnih proteina, što je posledica presecanja -SQNY-PIVQ- motiva
Ovaj enzim pripada peptidaznoj familiji A2.
Reference
уреди- ^ Towler, E.M., Gulnik, S.V., Bhat, T.N., Xie, D., Gustschina, E., Sumpter, T.R., Robertson, N., Jones, C., Sauter, M., Mueller-Lantzsch, N., Debouck, C. and Erickson, J.W. (1998). „Functional characterization of the protease of human endogenous retrovirus, K10: can it complement HIV-1 protease”. Biochemistry. 37: 17137—17144. PMID 9860826.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
уреди- Human+endogenous+retrovirus+K+endopeptidase на US National Library of Medicine Medical Subject Headings (MeSH)
