Сахаропепсин
Saharopepsin (EC 3.4.23.25, kvašćana endopeptidaza A, Saccharomyces aspartinska proteinaza, aspartinska proteinaza yscA, proteinaza A, proteinaza yscA, kvašćana proteinaza A, Saccharomyces cerevisiae aspartinska proteinaza A, kvašćana proteinaza A, PRA) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Saharopepsin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.23.25 | ||||||||
| CAS broj | 37228-80-1 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Hidroliza proteina sa širokom specifičnošću za peptidne veze. Razlaže se -Leu-Leu-Val-Tyr veza u sintetičnim supstratime. Ne dolazi do reakcije na estrima Tyr ili Arg
Ovaj enzim je prisutan u vakuolama pekarskog kvasca (Saccharomyces cerevisiae).
Reference
уреди- ^ Hata, T., Hayashi, R. and Dot, E. (1967). „Purification of yeast proteinases. Part III. Isolation and physicochemical properties of yeast proteinase A and C”. Agric. Biol. Chem. 31: 357—367.
- ^ Meussdoerffer, F., Tortora, P. and Holzer, H. (1980). „Purification and properties of proteinase A from yeast”. J. Biol. Chem. 255: 12087—12093. PMID 7002931.
- ^ Ammerer, G., Hunter, C.P., Rothman, J.H., Saari, G.C., Valls, L.A. and Stevens, T.H. (1987). „PEP4 gene of Saccharomyces cerevisiae encodes proteinase A, a vacuolar enzyme required for processing of vacuolar precursors”. Mol. Cell. Biol. 6: 2490—2499. PMID 3023936.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
уреди- Saccharopepsin на US National Library of Medicine Medical Subject Headings (MeSH)
