Полимераза
Polimeraza (EC 2.7.7.6/7/19/48/49) je enzim čija centralna funkcije je formiranje polimera nukleinskih kiselina kao što su RNK i DNK.[1] Reakcija polimerizacije nove DNK ili RNK se izvodi koristeći postojeći DNK ili RNK templet u procesima replikacije i transkripcije. U sprezi sa klasterom drugih enzima i proteina, polimeraza koristi nukleotide iz rastvora, i katalizuje sintezu polinukleotidne sekvence sledeći lanac nukleotidnog templeta.[2]
Reference
уреди- ^ Donald Voet; Judith G. Voet (2005). Biochemistry (3 изд.). Wiley. ISBN 9780471193500.
- ^ Bruce Alberts; Alexander Johnson; Julian Lewis; Martin Raff; Keith Roberts; Peter Walter (2002). Molecular Biology of the Cell. New York: Garlard Science. ISBN 0815332181.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
