Леукоантоцијанидин редуктаза
Leukoantocijanidin reduktaza (EC 1.17.1.3, leuocijanidinsk reduktaza) je enzim sa sistematskim imenom (2R,3S)-katehin:NADP+ 4-oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Leukoantocijanidin reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.17.1.3 | ||||||||
| CAS broj | 776323-46-7 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- (2R,3S)-katehin + NADP+ + H2O 2,3-trans-3,4-cis-leuocijanidin + NADPH + H+
Ovaj enzim katalizuje sintezu katehina, katehin-4beta-ola (leuocijanidina) i srodnih flavan-3-ola: afzelehina i galokatehina.
Reference
уреди- ^ Tanner, G.J. & Kristiansen, K.N. (1993). „Synthesis of 3,4-cis-[3H]leucocyanidin and enzymatic reduction to catechin”. Anal. Biochem. 209: 274—277. PMID 8470799.
- ^ Tanner, G.J., Francki, K.T., Abrahams, S., Watson, J.M., Larkin, P.J. and Ashton, A.R. (2003). „Proanthocyanidin biosynthesis in plants: Purification of legume leucoanthocyanidin reductase and molecular cloning of its cDNA”. J. Biol. Chem. 278: 31647—31656. PMID 12788945.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
уреди- Leucoanthocyanidin+reductase на US National Library of Medicine Medical Subject Headings (MeSH)
