Tiazid

(преусмерено са Thiazides)

Tiazid je tip molekula[1] i klasa diuretika[2] koji se često koriste za tretiranje hipertenzije (visokog krvnog pristiska) i edema (poput onih uzrokovanih bolestima srca, jetre, ili bubrega).

Benzotiadiazin
Hlorotiazid
Hidrohlorotiazid

Tiazidi i tiazidima slični diuretici redukuju rizik od smrti, šloga, srčanog udara i zatajenja srca usled hipertenzije.[3] U većini zemalja, tiazidi su najjeftiniji antihipertenzivni lekovi.[4]

Reference

уреди
  1. ^ Thiazides на US National Library of Medicine Medical Subject Headings (MeSH)
  2. ^ Thiazide+Diuretics на US National Library of Medicine Medical Subject Headings (MeSH)
  3. ^ Wright JM, Musini VM (2009). Wright JM, ур. „First-line drugs for hypertension”. Cochrane Database Syst Rev. 8 (3): CD001841. PMID 19588327. doi:10.1002/14651858.CD001841.pub2. 
  4. ^ Whitworth, JA (2003). World Health Organization, International Society of Hypertension Writing Group. „2003 World Health Organization (WHO)/International Society of Hypertension (ISH) statement on management of hypertension”. J Hypertens. 21 (11): 1983—92. PMID 14597836. doi:10.1097/00004872-200311000-00002. 

Literatura

уреди
  • Bertram G. Katzung: Basic and Clinical Pharmacology. Kapitel 15 Diuretic agents. Mcgraw-Hill Professional. 9th Edition. 2004. ISBN 978-0-07-141092-2.
  • Donald W. Seldin (Hrsgb.), Gerhard Giebisch (Hrsgb.): Diuretic Agents: Clinical Physiology and Pharmacology. Kapitel 3 A history of diuretics, S. 3 ff. und Kapitel Academic Press. 1st edition. 1997. ISBN 978-0-12-635690-8.
  • Craig, Stitzel: Modern Pharmacology with Clinical Applications. Kapitel 21 Diuretic Drugs, S. 249 ff. Lippincott Raven, 6th Edition. 2003. ISBN 978-0-7817-3762-3.

Spoljašnje veze

уреди