Omega amidaza
Omega amidaza (EC 3.5.1.3, alfa-keto kiselina-omega-amidaza) je enzim sa sistematskim imenom omega-amidodikarboksilat amidohidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
Omega amidaza | |||||||||
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Identifikatori | |||||||||
EC broj | 3.5.1.3 | ||||||||
CAS broj | 9025-19-8 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- Monoamid dikarboksilne kiseline + H2O dikarboksilat + NH3
Ovaj enzim deluje na glutaramat, sukcinamat i njihove 2-okso derivate.
Reference
уреди- ^ Meister, A., Levintow, L., Greenfield, R.E. and Abendschein, P.A. (1955). „Hydrolysis and transfer reactions catalyzed by ω-amidase preparations”. J. Biol. Chem. 215: 441—460. PMID 14392177.
- ^ Meister, A., Radhakrishnan, A.N. and Buckley, S.D. (1957). „Enzymatic synthesis of L-pipecolic acid and L-proline”. J. Biol. Chem. 229: 789—800. PMID 13502341.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
уреди- Omega-amidase на US National Library of Medicine Medical Subject Headings (MeSH)