Lipoproteinska lipaza
(преусмерено са Lipoprotein lipase)
Lipoproteinska lipaza (EC 3.1.1.34, digliceridna lipaza, diacilglicerolna lipaza, postheparinska esteraza, digliceridna lipaza, postheparinska lipaza, diacilglicerolna hidrolaza) je enzim sa sistematskim imenom triacilglicero-protein acilhidrolaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Lipoproteinska lipaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.1.34 | ||||||||
| CAS broj | 2594722 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- triacilglicerol + H2O diacilglicerol + karboksilat
Ovaj enzim hidrolizuje triacilglicerole u hilomikronima i lipoproteinima niske gustine. On takođe hidrolizuje diacilglicerol.
Reference
уреди- ^ Egelrud, T. & Olivecrona, T. (1973). „Purified bovine milk (lipoprotein) lipase: activity against lipid substrates in the absence of exogenous serum factors”. Biochim. Biophys. Acta. 306: 115—127. PMID 4703566.
- ^ Fielding, C.J. (1970). „Human lipoprotein lipase. I. Purification and substrate specificity”. Biochim. Biophys. Acta. 206: 109—117. PMID 5441398.
- ^ Greten, H., Levy, R.I., Fales, H. and Fredrickson, D.S. (1970). „Hydrolysis of diglyceride and glyceryl monoester diethers with lipoprotein lipase”. Biochim. Biophys. Acta. 210: 39—45. PMID 5466051.
- ^ Morley, N. & Kuksis, A. (1972). „Positional specificity of lipoprotein lipase”. J. Biol. Chem. 247: 6389—6393. PMID 5076762.
- ^ Nilsson-Ehle, P., Belfrage, P. and Borgström, B. (1971). „Purified human lipoprotein lipase: positional specificity”. Biochim. Biophys. Acta. 248: 114—120. PMID 5168777.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
уреди- Lipoprotein+lipase на US National Library of Medicine Medical Subject Headings (MeSH)
