Kariofilen

Kariofilen
Nazivi
	IUPAC nazivs 4,11,11-trimetil-8-metilen-; biciklo[7.2.0]undek-4-en
	Drugi nazivi β-Kariofilen; ; trans-(1R,9S)-8-Metilen-4,11,11-trimetilbiciklo[7.2.0]undek-4-en
Identifikacija
CAS broj	87-44-5 ;
3D model (Jmol)	interaktivna slika;
ChEBI	CHEBI:10357 ;
ChemSpider	4444848 ;
ECHA InfoCard	100.001.588
PubChem C ID	5281515;
UNII	BHW853AU9H ;
	SMILES C1(=C)\CC/C=C(/CC[C@@H]2[C@@H]1CC2(C)C)C; ; ; ; ; ;
Svojstva
Hemijska formula	C15H24
Molarna masa	204,36 g/mol
Gustina	0,9052 g/cm3
Tačka ključanja	262-264°C; 129-130 °C (14 mm Hg)
	Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa).
	verifikuj (šta je ?)
	Reference infokutije

Kariofilen ((−)-β-kariofilen) je prirodni biciklični seskviterpen koji je sastojak mnogih esencijalnih ulja, posebno ulja karanfilića, koje se pravi od stabljika i cveća biljke Syzygium aromaticum (klinčić),^[3] eteričnog ulja od konoplje Cannabis sativa,^[4] ruzmarina Rosmarinus oficinalis,^[5] i hmelja.^[6] On se obično nalazi kao smeša sa izokariofilenom (cis izomerom dvostruke veze) i α-humulenom (α-kariofilenom), izomerom sa otvorenim prstenom. Kariofilen je karakterističan po ciklobutanskom prstenu, koji se retko sreće u prirodi.

Reference

^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003. уреди
^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1.
^ Ghelardini C, Galeotti N, Di Cesare Mannelli L, Mazzanti G, Bartolini A (2001). „Local anaesthetic activity of beta-caryophyllene”. Farmaco. 56 (5–7): 387—9. PMID 11482764. doi:10.1016/S0014-827X(01)01092-8.
^ Gertsch J; Leonti M; Raduner S; et al. (2008). „Beta-caryophyllene is a dietary cannabinoid”. Proceedings of the National Academy of Sciences of the United States of America. 105 (26): 9099—104. PMC 2449371  . PMID 18574142. doi:10.1073/pnas.0803601105.
^ Ormeño E, Baldy V, Ballini C, Fernandez C (2008). „Production and diversity of volatile terpenes from plants on calcareous and siliceous soils: effect of soil nutrients”. J. Chem. Ecol. 34 (9): 1219—29. PMID 18670820. doi:10.1007/s10886-008-9515-2.
^ Glenn Tinseth, "Hop Aroma and Flavor", January/February 1993, Brewing Techniques. <http://realbeer.com/hops/aroma.html> Accessed July 21, 2010.

Spoljašnje veze

"Some Proof that Marijuana is a Powerful Medicine", Aaron Rowe, Wired Magazine, June 29, 2008

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003. уреди

[2] Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1.

[pmid11482764-3] Ghelardini C, Galeotti N, Di Cesare Mannelli L, Mazzanti G, Bartolini A (2001). „Local anaesthetic activity of beta-caryophyllene”. Farmaco. 56 (5–7): 387—9. PMID 11482764. doi:10.1016/S0014-827X(01)01092-8.

[pmid18574142-4] Gertsch J; Leonti M; Raduner S; et al. (2008). „Beta-caryophyllene is a dietary cannabinoid”. Proceedings of the National Academy of Sciences of the United States of America. 105 (26): 9099—104. PMC 2449371  . PMID 18574142. doi:10.1073/pnas.0803601105.

[pmid18670820-5] Ormeño E, Baldy V, Ballini C, Fernandez C (2008). „Production and diversity of volatile terpenes from plants on calcareous and siliceous soils: effect of soil nutrients”. J. Chem. Ecol. 34 (9): 1219—29. PMID 18670820. doi:10.1007/s10886-008-9515-2.

[6] Glenn Tinseth, "Hop Aroma and Flavor", January/February 1993, Brewing Techniques. <http://realbeer.com/hops/aroma.html> Accessed July 21, 2010.

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Nazivi

IUPAC nazivs 4,11,11-trimetil-8-metilen- biciklo[7.2.0]undek-4-en
Drugi nazivi β-Kariofilen; trans-(1R,9S)-8-Metilen-4,11,11-trimetilbiciklo[7.2.0]undek-4-en
Identifikacija
CAS broj	87-44-5^Y
3D model (Jmol)	interaktivna slika
ChEBI	CHEBI:10357^Y
ChemSpider	4444848^Y
ECHA InfoCard	100.001.588
PubChem^[1]^[2] C ID	5281515
UNII	BHW853AU9H^Y

SMILES C1(=C)\CC/C=C(/CC[C@@H]2[C@@H]1CC2(C)C)C
Svojstva
Hemijska formula	C₁₅H₂₄
Molarna masa	204,36 g/mol
Gustina	0,9052 g/cm³
Tačka ključanja	262-264°C; 129-130 °C (14 mm Hg)
Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa).
Y verifikuj (šta je ^YН ?)
Reference infokutije