Fenoterol

Fenoterol je organsko jedinjenje, koje sadrži 17 atoma ugljenika i ima molekulsku masu od 303,353 Da.^[1]^[2]

Fenoterol
Klinički podaci


Drugs.com	Monografija
Način primene	Respiratorno (inhalacija)
Identifikatori
CAS broj	13392-18-2^Y
ATC kod	R03CC04 (WHO), R03AC04
PubChem	CID 3343
IUPHAR/BPS	557
DrugBank	DB01288^Y
ChemSpider	3226^Y
ChEBI	CHEBI:149226^Y
ChEMBL	CHEMBL32800^Y
Hemijski podaci
Formula	C₁₇H₂₁NO₄
Molarna masa	303,353
SMILES CC(CC1=CC=C(O)C=C1)NCC(O)C1=CC(O)=CC(O)=C1
InChI InChI=1S/C17H21NO4/c1-11(6-12-2-4-14(19)5-3-12)18-10-17(22)13-7-15(20)9-16(21)8-13/h2-5,7-9,11,17-22H,6,10H2,1H3^Y Key:LSLYOANBFKQKPT-UHFFFAOYSA-N^Y

Osobine

Osobina	Vrednost
Broj akceptora vodonika	5
Broj donora vodonika	5
Broj rotacionih veza	6
Particioni koeficijent^[3] (ALogP)	2,4
Rastvorljivost^[4] (logS, log(mol/L))	-3,2
Polarna površina^[5] (PSA, Å²)	93,0

Reference

^ Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs”. Nucleic Acids Res. 39 (Database issue): D1035—41. PMC 3013709  . PMID 21059682. doi:10.1093/nar/gkq1126.
^ David S. Wishart; Craig Knox; An Chi Guo; Dean Cheng; Savita Shrivastava; Dan Tzur; Bijaya Gautam; Murtaza Hassanali (2008). „DrugBank: a knowledgebase for drugs, drug actions and drug targets”. Nucleic acids research. 36 (Database issue): D901—6. PMC 2238889  . PMID 18048412. doi:10.1093/nar/gkm958.
^ Ghose, A.K.; Viswanadhan V.N. & Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods”. J. Phys. Chem. A. 102: 3762—3772. doi:10.1021/jp980230o.
^ Tetko IV, Tanchuk VY, Kasheva TN, Villa AE (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”. Chem Inf. Comput. Sci. 41: 1488—1493. PMID 11749573. doi:10.1021/ci000392t.
^ Ertl P.; Rohde B.; Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties”. J. Med. Chem. 43: 3714—3717. PMID 11020286. doi:10.1021/jm000942e.

Literatura

Hardman JG, Limbird LE, Gilman AG (2001). Goodman & Gilman's The Pharmacological Basis of Therapeutics (10. изд.). New York: McGraw-Hill. ISBN 0071354697. doi:10.1036/0071422803.
Thomas L. Lemke; David A. Williams, ур. (2007). Foye's Principles of Medicinal Chemistry (6. изд.). Baltimore: Lippincott Willams & Wilkins. ISBN 0781768799.

Spoljašnje veze

Fenoterol

Molimo Vas, obratite pažnju na važno upozorenje
u vezi sa temama iz oblasti medicine (zdravlja).

Преузето из „https://sr.wiki.x.io/w/index.php?title=Fenoterol&oldid=27604433”