F-12,826
F-12,826 je agonist 5-HT1A receptora.[3] Studije su pokazale da ligandi 5-HT1A receptora modulišu katalepsiju izazvanu antipsihoticima.
Nazivi | |
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Preferisani IUPAC naziv
2-[4-[4-(2-hidroksifenil)piperazin-1-il]butil]-4-metil-1,2,4-triazin-3,5-dion | |
Drugi nazivi
CHEMBL3330609 • 903528-73-4 • SCHEMBL4546516 • VFFKDKDNXHSXLX-UHFFFAOYSA-N • MFCD13182401
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Identifikacija | |
3D model (Jmol)
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Svojstva | |
C18H25N5O3 | |
Molarna masa | 359,43 g·mol−1 |
Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa). | |
Reference infokutije | |
Reference
уреди- ^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.
- ^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1.
- ^ Eric P M Prinssen; Francis C Colpaert; Wouter Koek (2002-10-25). „5-HT1A receptor activation and anti-cataleptic effects: high-efficacy agonists maximally inhibit haloperidol-induced catalepsy”. Eur J Pharmacol. 453 (2-3): 217—21. doi:10.1016/s0014-2999(02)02430-5.