Dipeptidaza E
Dipeptidaza E (EC 3.4.13.21, aspartilna dipeptidaza, peptidaza E, PepE genski produkt (Salmonella typhimurium)) je enzim.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Dipeptidaza E | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.13.21 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Dipeptidaza E katalizuje hidrolizu dipeptida Asp-Xaa. Ona ne deluje na peptide sa N-terminalnim Glu, Asn ili Gln, niti razlaže izoaspartilne peptide
Slobodna karboksi grupa nije apsolutno neophodna u supstratu.
Reference
уреди- ^ Haakansson, K., Wang, A.H.J. and Miller, C.G. (2000). „The structure of aspartyl dipeptidase reveals a unique fold with a Ser-His-Glu catalytic triad”. Proc. Natl. Acad. Sci. USA. 97: 14097—14102. PMID 11106384.
- ^ Lassy, R.A.L. & Miller, C.G. (2000). „Peptidase E, a peptidase specific for N-terminal aspartic dipeptides, is a serine hydrolase”. J. Bacteriol. 182: 2536—2543. PMID 10762256.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
уреди- Dipeptidase+E на US National Library of Medicine Medical Subject Headings (MeSH)
