CXCL17
CXCL17, hemokin (C-X-C motiv) ligand 17, je mali citokin iz CXC hemokin familije koji je bio identifikovan kod ljudi i miševa. CXCL17 privlači dendritske ćelije i monocite. On je takođe poznat kao VEGF koregulisani hemokin 1 (VCC-1) i hemokinu-sličan protein koji privlači dendritske ćelije i monocite (engl. dendritic cell- and monocyte-attracting chemokine-like protein) (DMC).[1][2] Ovaj hemokin je konstitutivno izražen u plućima.[2] Gen za ljudski CXCL17 je lociran na hromozom 19.[2][3]
Hemokine (C-X-C motiv) ligand 17 | |
---|---|
Identifikatori | |
Simbol | CXCL17 |
Alt. simboli | SCYB17, VCC-1, DMC |
Entrez | 284340 |
RefSeq | NM_198477 |
UniProt | Q6UXB2 |
Ostali podaci | |
Lokus | Hromozom 19 q13.2 |
Reference
уреди- ^ Weinstein E, Head R, Griggs D, Sun D, Evans R, Swearingen M, Westlin M, Mazzarella R (2006). „VCC-1, a novel chemokine, promotes tumor growth”. Biochem Biophys Res Commun. 350 (1): 74—81. PMID 16989774. doi:10.1016/j.bbrc.2006.08.194.
- ^ а б в Pisabarro M, Leung B, Kwong M, Corpuz R, Frantz G, Chiang N, Vandlen R, Diehl L, Skelton N, Kim H, Eaton D, Schmidt K (2006). „Cutting edge: novel human dendritic cell- and monocyte-attracting chemokine-like protein identified by fold recognition methods”. J Immunol. 176 (4): 2069—73. PMID 16455961.
- ^ Mire-Sluis, Anthony R.; Thorpe, Robin, ур. (1998). Cytokines (Handbook of Immunopharmacology). Boston: Academic Press. ISBN 0-12-498340-5.