CHST1

CHST1 (eng. Carbohydrate sulfotransferase 1) je enzim koji je kod ljudi kodiran genom CHST1, nalazi se na kratkom (p) kraku 11. hromozoma. Dužina polipeptidnog lanca proteina je 411 aminokiselina, a molekulska masa je 46.715..

CHST1
Identifikatori
Alijasi	CHST1
Spoljašnji ID	OMIM: 603797 MGI: 1924219 HomoloGene: 2711 GeneCards: CHST1
Genska lokacija (miš) Hr. Chromosome 2 (mouse) Band 2|2 E1 Start 92,430,052 bp Kraj 92,445,595 bp
Obrazac RNK izražavanja More reference expression data
Genska ontologija Molecular function • transferase activity • sulfotransferase activity • N-acetylglucosamine 6-O-sulfotransferase activity • keratan sulfotransferase activity Cellular component • Golgi membrane • Голџијев апарат • мембрана • саставни део мембране • trans-Golgi network Biological process • sulfur compound metabolic process • galactose metabolic process • запаљенска реакција • keratan sulfate biosynthetic process • polysaccharide metabolic process • keratan sulfate metabolic process • Метаболизам угљених хидрата • N-acetylglucosamine metabolic process Sources:Amigo / QuickGO
Ortolozi
Vrste	Čovek	Miš
Entrez	8534	76969
Ensembl	ENSG00000175264	ENSMUSG00000027221
UniProt	O43916	Q9EQC0
RefSeq (mRNA)	NM_003654	NM_023850 NM_001356552 NM_001356553
RefSeq (protein)	NP_003645	NP_076339 NP_001343481 NP_001343482
Location (UCSC)	n/a	Chr 2: 92.43 – 92.45 Mb
PubMed search
Wikidata
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Dopunska literatura

• Williams KJ (1997). „Atherosclerosis: cell biology and lipoproteins.”. Curr. Opin. Lipidol. 7 (6): U202—8. PMID 9117134. doi:10.1097/00041433-199612000-00016. 
• Bernstein HB, Compans RW (1992). „Sulfation of the human immunodeficiency virus envelope glycoprotein.”. J. Virol. 66 (12): 6953—9. PMC 240329 . PMID 1433500. doi:10.1128/JVI.66.12.6953-6959.1992. 
• Shilatifard A, Merkle RK, Helland DE, et al. (1993). „Complex-type N-linked oligosaccharides of gp120 from human immunodeficiency virus type 1 contain sulfated N-acetylglucosamine.”. J. Virol. 67 (2): 943—52. PMC 237448 . PMID 8419650. doi:10.1128/JVI.67.2.943-952.1993. 
• Li X, Tedder TF (1999). „CHST1 and CHST2 sulfotransferases expressed by human vascular endothelial cells: cDNA cloning, expression, and chromosomal localization.”. Genomics. 55 (3): 345—7. PMID 10049591. doi:10.1006/geno.1998.5653. 
• Bistrup A, Bhakta S, Lee JK, et al. (1999). „Sulfotransferases of two specificities function in the reconstitution of high endothelial cell ligands for L-selectin.”. J. Cell Biol. 145 (4): 899—910. PMC 2133194 . PMID 10330415. doi:10.1083/jcb.145.4.899. 
• Tu L, Murphy PG, Li X, Tedder TF (1999). „L-selectin ligands expressed by human leukocytes are HECA-452 antibody-defined carbohydrate epitopes preferentially displayed by P-selectin glycoprotein ligand-1.”. J. Immunol. 163 (9): 5070—8. PMID 10528213. doi:10.4049/jimmunol.163.9.5070. 
• Torii T, Fukuta M, Habuchi O (2000). „Sulfation of sialyl N-acetyllactosamine oligosaccharides and fetuin oligosaccharides by keratan sulfate Gal-6-sulfotransferase.”. Glycobiology. 10 (2): 203—11. PMID 10642612. doi:10.1093/glycob/10.2.203 . 
• Li X, Tu L, Murphy PG, et al. (2001). „CHST1 and CHST2 sulfotransferase expression by vascular endothelial cells regulates shear-resistant leukocyte rolling via L-selectin.”. J. Leukoc. Biol. 69 (4): 565—74. PMID 11310842. S2CID 8888883. doi:10.1189/jlb.69.4.565 . 
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899—903. Bibcode:2002PNAS...9916899M. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899 . 
• Yamada T, Ohtake S, Sato M, Habuchi O (2005). „Chondroitin 4-sulphotransferase-1 and chondroitin 6-sulphotransferase-1 are affected differently by uronic acid residues neighbouring the acceptor GalNAc residues.”. Biochem. J. 384 (Pt 3): 567—75. PMC 1134142 . PMID 15324304. doi:10.1042/BJ20040965. 
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res. 14 (10B): 2121—7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504. 
• Rual JF, Venkatesan K, Hao T, et al. (2005). „Towards a proteome-scale map of the human protein-protein interaction network.”. Nature. 437 (7062): 1173—8. Bibcode:2005Natur.437.1173R. PMID 16189514. S2CID 4427026. doi:10.1038/nature04209. 
• Liu J, Chau CH, Liu H, et al. (2006). „Upregulation of chondroitin 6-sulphotransferase-1 facilitates Schwann cell migration during axonal growth.”. J. Cell Sci. 119 (Pt 5): 933—42. PMID 16495484. doi:10.1242/jcs.02796 . hdl:10722/44575 . 
• Kitayama K, Hayashida Y, Nishida K, Akama TO (2007). „Enzymes responsible for synthesis of corneal keratan sulfate glycosaminoglycans.”. J. Biol. Chem. 282 (41): 30085—96. PMID 17690104. doi:10.1074/jbc.M703695200 .