Aminoacilaza
Aminoacilaza (EC 3.5.1.14, dehidropeptidaza II, histozim, hipurikaza, benzamidaza, acilaza I, hipuraza, amidokiselinska deacilaza, L-aminoacilaza, acilaza, aminoacilaza I, L-aminokiselinska acilaza, alfa-N-acilaminokiselinska hidrolaza, dugoacilna amidoacilaza, kratkoacilna amidoacilaza) je enzim sa sistematskim imenom N-acil-L-amino-kiselina amidohidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Aminoacilaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.5.1.14 | ||||||||
| CAS broj | 9012-37-7 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- N-acil-L-aminokiselina + H2O karboksilat + L-aminokiselina
Ovaj enzim ima široku specifičnost. On takođe hidrolizuje dehidropeptide.
Reference
уреди- ^ Birnbaum, S.M., Levintow, L., Kingsley, R.B. and Greenstein, J.P. (1952). „Specificity of amino acid acylases”. J. Biol. Chem. 194: 455—470. PMID 14927637.
- ^ Fones, W.S. & Lee, M. (1953). „Hydrolysis of N-acyl derivatives of alanine and phenylalanine by acylase I and carboxypeptidase”. J. Biol. Chem. 201: 847—856. PMID 13061423.
- ^ Park, R.W. & Fox, S.W. (1960). „An acylase system related to the utilization of benzoylamino acids by Lactobacillus arabinosus”. J. Biol. Chem. 235: 3193—3197. PMID 13732833.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
уреди- Aminoacylase на US National Library of Medicine Medical Subject Headings (MeSH)
