Alanin dehidrogenaza
Alanin dehidrogenaza (EC 1.4.1.1, AlaDH, L-alaninska dehidrogenaza, NAD+-vezana alaninska dehidrogenaza, alfa-alaninska dehidrogenaza, NAD+-zavisna alaninska dehidrogenaza, alaninska oksidoreduktaza, NADH-zavisna alaninska dehidrogenaza) je enzim sa sistematskim imenom L-alanin:NAD+ oksidoreduktaza (deaminacija).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Alanin dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.4.1.1 | ||||||||
| CAS broj | 2603971 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- L-alanin +H2O + NAD+ piruvat + NH3 + NADH + H+
Reference
уреди- ^ O'Connor, R.J. & Halvorson, H. (1961). „The substrate specificity of L-alanine dehydrogenase”. Biochim. Biophys. Acta. 48: 47—55. PMID 13730044.
- ^ Piérard, A. and Wiame, J.M. (1960). „Propriétés de la L(+)-alanine-déshydrogénase”. Biochim. Biophys. Acta. 37: 490—502. PMID 14432812.
- ^ Yoshida, A. & Freese, E. (1965). „Enzymic properties of alanine dehydrogenase of Bacillus subtilis”. Biochim. Biophys. Acta. 96: 248—262. PMID 14298830.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
уреди- Alanine+dehydrogenase на US National Library of Medicine Medical Subject Headings (MeSH)
