ATP fosforiboziltransferaza

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PMC	članci
PubMed	članci
NCBI	proteini

ATP fosforiboziltransferaza
ATP fosforiboziltransferaza
Identifikatori
EC broj	2.4.2.17
CAS broj	9031-46-3
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

ATP fosforiboziltransferaza (EC 2.4.2.17, fosforibozil-ATP pirofosforilaza, adenozin trifosfat fosforiboziltransferaza, fosforiboziladenozin trifosfat:pirofosfat fosforiboziltransferaza, fosforibozil ATP sintetaza, fosforibozil ATP:pirofosfat fosforiboziltransferaza, fosforibozil-ATP:pirofosfat-fosforibozil fosfotransferaza, fosforiboziladenozin trifosfat pirofosforilaza, fosforiboziladenozin trifosfat sintetaza) je enzim sa sistematskim imenom 1-(5-fosfo-D-ribozil)-ATP:difosfat fosfo-alfa-D-ribozil-transferaza.^[1]^[2]^[3] Ovaj enzim katalizuje sledeću hemijsku reakciju

1-(5-fosfo-D-ribozil)-ATP + difosfat

\rightleftharpoons

ATP + 5-fosfo-alfa-D-riboza 1-difosfat

Reference

^ Ames, B.N., Martin, R.G. and Garry, B.J. (1961). „The first step of histidine biosynthesis”. J. Biol. Chem. 236: 2019—2026. PMID 13682989.
^ Martin, R.G. (1963). „The phosphorolysis of nucleosides by rabbit bone marrow: The nature of feedback inhibition by histidine”. J. Biol. Chem. 238: 257—268.
^ Voll, M.J., Appella, E. and Martin, R.G. (1967). „Purification and composition studies of phosphoribosyladenosine triphosphate:pyrophosphate phosphoribosyltransferase, the first enzyme of histidine biosynthesis”. J. Biol. Chem. 242: 1760—1767. PMID 5337591.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

ATP+phosphoribosyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Ames, B.N., Martin, R.G. and Garry, B.J. (1961). „The first step of histidine biosynthesis”. J. Biol. Chem. 236: 2019—2026. PMID 13682989.

[2] Martin, R.G. (1963). „The phosphorolysis of nucleosides by rabbit bone marrow: The nature of feedback inhibition by histidine”. J. Biol. Chem. 238: 257—268.

[3] Voll, M.J., Appella, E. and Martin, R.G. (1967). „Purification and composition studies of phosphoribosyladenosine triphosphate:pyrophosphate phosphoribosyltransferase, the first enzyme of histidine biosynthesis”. J. Biol. Chem. 242: 1760—1767. PMID 5337591.

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