2-(acetamidometiln)sukcinatna hidrolaza
2-(acetamidometiln)sukcinatna hidrolaza (EC 3.5.1.29, alfa-(N-acetilaminometilin)sukcinsko kiselinska hidrolaza) je enzim sa sistematskim imenom 2-(acetamidometilin)sukcinat amidohidrolaza (deaminacija, dekarboksilacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| 2-(acetamidometiln)sukcinatna hidrolaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.5.1.29 | ||||||||
| CAS broj | 37289-09-1 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 2-(acetamidometilin)sukcinat + 2H2O acetat + sukcinat semialdehid + NH3 + CO2
Ovaj enzim učestvuje u degradaciji piridoksina u Pseudomonas.
Reference
уреди- ^ Huynh, M.S. & Snell, E.E. (1985). „Enzymes of vitamin B6 degradation. Purification and properties of two N-acetylamidohydrolases”. J. Biol. Chem. 260: 2379—2383. PMID 3972793.
- ^ Nyns, E.J., Zach, D. and Snell, E.E. (1969). „The bacterial oxidation of vitamin B6. 8. Enzymatic breakdown of α-(N-acetylaminomethylene) succinic acid”. J. Biol. Chem. 244: 2601—2605. PMID 5769993.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
уреди- 2-(acetamidomethylene)succinate+hydrolase на US National Library of Medicine Medical Subject Headings (MeSH)
