Алкилглицерон-фосфат синтаза
Alkilgliceron-fosfat sintaza (EC 2.5.1.26, alkildihidroksiacetonfosfatna sintaza, alkildihidroksiaceton fosfatna sintetaza, alkil DHAP sintetaza, alkil-DHAP, dihidroksiaceton-fosfatna aciltransferaza, DHAP-AT) je enzim sa sistematskim imenom 1-acil-gliceron-3-fosfat:dugolančani-alkohol O-3-fosfo-2-oksopropaniltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Alkilgliceron-fosfat sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.5.1.26 | ||||||||
| CAS broj | 102484-74-2&title= 64060-42-0, 102484-74-2 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 1-acil-gliceron 3-fosfat + dugolančani alkohol alkil-gliceron 3-fosfat + dugolančani kiselinski anion
Estarski vezana masna kiselina supstrata se odvaja i zamenjuje dugolančanim alkoholom etarski vezanim.
Reference
уреди- ^ Brown, A.J. & Snyder, F. (1982). „Alkyldihydroxyacetone-P synthase. Solubilization, partial purification, new assay method, and evidence for a ping-pong mechanism”. J. Biol. Chem. 257: 8835—8839. PMID 7096336.
- ^ Wykle, R.L., Piantadosi, C. and Snyder, F. (1972). „The role of acyldihydroxyacetone phosphate, reduced nicotinamide adenine dinucleotide, and reduced nicotinamide adenine dinucleotide phosphate in the biosynthesis of O-alkyl glycerolipids by microsomal enzymes of Ehrlich ascites tumor”. J. Biol. Chem. 247: 2944—2948. PMID 4401994.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
уреди- Alkylglycerone-phosphate+synthase на US National Library of Medicine Medical Subject Headings (MeSH)
